Welcome to Andrew Prayle’s github pages site. On this site you will find links to the various evidence maps we have created.
The following evidence maps were commissioned as part of grants supporting the work of CochraneCF.
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis (status: evidence map completed and available online). Click here for the Pseudomonal eradication therapy evidence map.
Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis (status: review updated, no evidence map in preparation)
Interventions for the eradication of methicillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis (status: evidence map completed and available online). Click here for the MRSA evidence map.
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (status:review updated, no evidence map yet)
Macrolide antibiotics for cystic fibrosis (status: evidence map completed and available online). Click here for the macrolide evidence map.
Infection prevention and control in cystic fibrosis Click here to go to the interactive figure for Rowbotham, N. J., Smith, S., Jahnke, N., Milczanowski, S., Elliott, Z. C., Prayle, A. P., & Smyth, A. R. (2025). Infection prevention and control in cystic fibrosis: An update of a systematic review of interventions. Journal of Cystic Fibrosis, 24(2), 359-363. https://doi.org/10.1016/j.jcf.2024.08.004
Antibiotic treatment for nontuberculous mycobacteria lung infection in people with cystic fibrosis (status: review updated, no evidence map yet)
Non-antibiotic treatment for nontuberculous mycobacteria lung infection in people with cystic fibrosis (status: review completed & submitted to BMJ Open Respiratory Research, evidence map in preparation)
Lung transplant in people with CF and NTM pulmonary disease (status: review almost completed, awaiting evidence map)
Institutional or domestic interventions to reduce water-borne transmission of nontuberculous mycobacteria (NTM) (status: review should be completed by mid-May, no evidence map yet)
Click here to go to the interactive figure from Prayle AP, Cox T, Smith SJ, et al. Do guidelines for treating chest disease in children use Cochrane Reviews effectively? A systematic review. Thorax. 2018;73:670-3.
Click here to go to the interactive figure from Rowbotham NJ, Smith S, Prayle AP, Robinson KA, Smyth AR. Gaps in the evidence for treatment decisions in cystic fibrosis: a systematic review. Thorax. 2019;74:229-36.
The current evidence map version is 0.053.